Geographic patterns of cancer in the population-based registry of Egypt: Possible links to environmental exposures
A partir des données d’un registre du cancer égyptien, cette étude analyse, pour les 10 cancers les plus fréquents, les disparités géographiques d’incidence et évalue leur association avec des expositions à des facteurs de risque environnementaux
Background: We investigated the variation in cancer incidence in Gharbiah, Egypt to explore geographic differences in relation to demographic and environmental exposures. Methods: Using data from the only population-based cancer registry of Gharbiah, we studied the 10 most common cancers in men and women over 4 years (1999-2002). Census data provided denominators and urban-rural definitions. Crude and adjusted incidence rates (IRs), incidence rate ratios (IRRs) and 95% confidence intervals (CIs) were estimated using Poisson regression. Results: Incidence of all common cancers was higher among men than women and urban incidence was higher than rural incidence for all cancer sites. Among men and women urban-rural incidence difference was highest for prostate cancer (IRR = 4.85, 95% CI = 3.76, 6.26) and uterus (IRR = 6.05, 95% CI = 4.17, 8.78), respectively. Among men and women, El-Santa district had the highest urban-rural difference within districts for laryngeal cancer (IRR = 29.45, 95% CI = 10.63, 81.61) and uterine cancer (IRR = 15.98, 95% CI = 2.69, 95.10), respectively. El-Santa also showed the highest urban incidence among all eight districts for most cancer sites. Conclusions: Geographic differences of cancers in Gharbiah need in-depth investigation with respect to specific environmental factors that explain the geographic cancer in this region.
Cancer Epidemiology 2011