Targeting Cytotoxic T Cells to Tumor
Cette étude évalue l'intérêt d'une immunothérapie à base de lymphocytes CAR-T autologues ciblant la mutation G12D du gène KRAS chez une patiente atteinte d'un cancer métastatique du pancréas
This explanatory editorial elucidates the components and concepts behind a study, described in this issue of the Journal, that involves therapeutic targeting of pancreatic cancer with an autologous T cell engineered to have exquisite specificity for targeting the cancer cell.
New England Journal of Medicine , éditorial, 2021