The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection
Cet article passe en revue les connaissances concernant les cancers colorectaux de survenue précoce : données épidémiologiques, caractéristiques cliniques et biologiques, facteurs de risque, stratégies de prévention et de dépistage précoce
The incidence of early-onset colorectal—ie, colorectal cancer cancer diagnosed in patients under the age of 50 years— has been increasing around the world. This Series paper provides a comprehensive review on the topic of early-onset colorectal cancer, including examining the epidemiology of early-onset colorectal cancer around the world, clinical and pathological features, genetic and epigenetic landscapes, and emerging data on the clinical risk factors associated with early-onset colorectal cancer. Evidence-based approaches to prevention and early detection are also presented.
The Lancet Gastroenterology & Hepatology , résumé, 2021