Association of intraoperative radiotherapy in the treatment of early-stage breast cancer with minor surgical site complications in oncoplastic breast-conserving surgery
Menée à partir de données portant sur 453 patientes atteintes d'un cancer du sein de stade précoce traité par chirurgie conservatrice, cette étude évalue, du point de vue du taux de complications mineures au niveau du site chirurgical dans les 6 mois qui suivent l'intervention, l'intérêt d'une radiothérapie intra-opératoire par rapport à une radiothérapie adjuvante de l'ensemble du sein
Breast-conserving therapy is a standard treatment option for patients with early-stage breast cancer, as large randomized studies have demonstrated equivalent overall and disease-free survival compared with mastectomy. Currently, breast-conserving therapy consists of surgical removal of the tumor and axillary staging followed by adjuvant whole-breast radiotherapy (WBRT). Through incorporation of plastic surgery techniques, oncoplastic breast-conserving surgery (OBCS) improves oncologic outcomes while improving cosmesis and reducing rates of postoperative reexcision, complications, and mastectomy. Breast-conserving therapy requires prolonged treatment owing to daily WBRT, which poses logistical impediments for some patients.
JAMA Surgery 2017