One-stage versus two-stage breast reconstruction: prudence in surgical decision-making
Mené sur 142 patientes atteintes d'un cancer du sein, cet essai multicentrique de phase IV compare, du point de vue de la qualité de vie et de la sécurité des patientes, l'intérêt de deux techniques de reconstruction mammaire par implant, l'une réalisée immédiatement après la mastectomie à l'aide d'une matrice dermique acellulaire, l'autre nécessitant deux interventions
Although approximately 70% of women with early-stage invasive breast cancer are candidates for breast-conserving surgery, many need and some choose to undergo mastectomy because of the extent of malignant disease in the breast, previous exposure to radiotherapy, contraindications or desire to avoid radiotherapy, to reduce the risk of subsequent breast cancers, or a combination of these factors. Additionally, the number of unilateral mastectomies for cancer treatment has been decreasing while that of bilateral mastectomies has been rising
The Lancet Oncology , commentaire, 2015