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Clinical Cancer Advances 2016: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology

Cet article décrit, du point de vue de l'American Society of Clinical Oncology, les principaux progrès dans la recherche clinique sur les cancers en 2015

In 2015, approximately 1.7 million Americans received a cancer diagnosis.1 In 2030, this number will rise to nearly 2.3 million.2 Today, approximately two of three Americans will live at least 5 years after being diagnosed with an invasive cancer.3
In addition, with care that aims to balance effectiveness of treatment alongside the importance of quality of life, more patients than ever are not just living longer but able to lead full lives. Yet, cancer remains a leading cause of death in the United States, claiming approximately 600,000 lives in 2015.1
On a global level, cancer is now one of the world’s most pressing health challenges. Seven of every 10 cancer deaths occur in Africa, Asia, and Central and South America. By the year 2030, these cancer deaths could increase globally by as much as 80%, according to WHO estimates.
The scientific community is working hard to avert this grim projection. Clinical research is the bedrock of progress against cancer, and discoveries are moving from bench to bedside faster than ever. The best example of this in recent years is the explosion of immunotherapy approaches for a variety of cancers.
Overall, research progress from one year to the next is incremental, and true breakthroughs are rare. Nevertheless, knowledge gathered from any single study can inform further research, and cumulative knowledge and progress result in tangible benefits for patients.
This report, “Clinical Cancer Advances 2016: Annual Report on Progress Against Cancer,” reviews the recent top advances and emerging trends in clinical cancer research. These advances are based on discoveries in cancer biology that are leading to improved cancer treatments for patients. Now in its 11th year, this report also highlights policy issues and developments that will affect the future of cancer research in the United States and determine the pace of progress going forward.

Journal of Clinical Oncology , article en libre accès, 2016

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