A calculating device to predict individualized outcomes in adrenocortical carcinoma
Menée sur 148 patients atteints d'un carcinome de la glande corticosurrénale traité par résection curative (âge médian : 53 ans ; 65,5 % de femmes), cette étude identifie des facteurs pronostiques puis évalue la performance de nomogrammes, basés sur la taille tumorale, l'envahissement ganglionnaire et la qualité des marges de résection, pour prédire la survie sans récidive ou la survie globale des patients
A nomogram is a 2-dimensional calculating device or alignment chart designed to allow the approximate computation of a function. The use of such a mathematical model for treatment of aggressive and rare diseases is objective and individualized. Like a slide rule, its accuracy is limited to the precision with which “markings” can be drawn and aligned. Kim, and colleagues1 have precisely described a coordinate system that can be easily reproduced to predict disease-free and overall survival after intended curative resection of adrenocortical carcinoma . The constants chosen were independent prognostic variables specific to the patient and the tumor.
JAMA Surgery , commentaire, 2014