Postmastectomy radiation therapy and breast reconstruction—marching forward together or apart ?
Menée à partir des données des registres américains des cancers portant sur 62 442 patientes atteintes d'un cancer du sein de stade I à III traité par mastectomie entre 2000 et 2011, cette étude évalue l'association entre l'évolution des recommandations du "National Comprehensive Cancer Network" et l'évolution de l'utilisation de la radiothérapie après l'intervention chirurgicale ainsi que le nombre de reconstructions mammaires pratiquées
Postmastectomy radiation therapy (PMRT) and immediate reconstruction each play important roles in the treatment of patients with breast cancer. Giving PMRT increases cure rates for subgroups with substantial risks of local-regional recurrence.1 Many individuals wish to have immediate breast reconstruction to reduce the psychological and social consequences of mastectomy. However, PMRT increases the risks of complications and poor cosmetic results after breast reconstruction. Immediate reconstruction limits the technical approaches available for delivering PMRT, potentially resulting in increased heart and lung doses. Improvements in surgical and radiation techniques over time have decreased but not entirely eliminated these problems.2,3
JAMA Oncology , commentaire, 2014