Minimal excess mortality for long-term colon cancer survivors in the Netherlands 1989–2008
A partir des données du registre néerlandais des cancers portant sur la période 1989 à 2008 (89 451 cas), cette étude analyse l'évolution de la mortalité de patients ayant survécu à long terme à un cancer du côlon
We determined conditional 5-year relative survival rates for colon cancer patients, according to age, gender and tumour stage for each additional year of survival up to 15years after diagnosis. All 89,451 patients diagnosed in the Netherlands with colon cancer stage I–III in 1989–2008 aged 15–89years were selected from the Netherlands Cancer Registry. Conditional 5-year relative survival was computed for every additional year of survival up to 15years. There was minimal excess mortality (conditional 5-year relative survival >95%) 1–4years after diagnosis of stage I patients and 4–7years after diagnosis of stage II patients, with patients aged 45–74years reaching this point later compared to both younger and elderly patients. For stage III patients, minimal excess mortality was observed 5years after diagnosis for those aged 75–89years, but it remained elevated up to 13years after diagnosis for those aged 15–44years. Initial differences in relative survival at diagnosis between age and stage groups largely disappeared with increasing number of years survived. The prognosis for colon cancer survivors improved with each additional year survived. In the first years after diagnosis conditional survival improved largely for all colon cancer patients, especially for stage III patients. There was minimal excess mortality for colon cancer patients stage I–III at some point within 15years of diagnosis, being later for more advanced stages. Quantitative insight into conditional survival for cancer patients is useful for caregivers to help plan optimal cancer surveillance and inform patients about their prognosis.
http://linkinghub.elsevier.com/retrieve/pii/S0959804912006624?showall=true 2012