Cancer and the Immune System
Cet article passe en revue les travaux récents sur les échanges entre le système immunitaire, inné et adaptatif, et les cellules tumorales
The immune system interacts with developing cancer in ways that can protect the host against hyperproliferation but that may also contribute to malignancy. Understanding the mechanisms behind the protective and harmful effects of the innate and adaptive immune systems in their exchanges with tumor cells will help to unravel how to harness our natural defenses with targeted therapeutics. This issue's Select delves into cancer immunoediting, T cell therapy, and how the goodies can become the baddies during tumor growth.
Cell , résumé, 2011